21st Century Medecine
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Title: In Memoriam - William F. Rall: Impacting science, impacting people
Author: G.M. Fahy, M. Wood, M. Hagerdorn
Citation: Cryobiology 120 (2025) 105292 (doi.org/10.1016/j.cryobiol.2025.105292)
Abstract: William Frederick Rall (Fig. 1) carried out many pioneering investigations on fundamental aspects of cryobiology, arguably culminating with his work on the successful vitrification of mouse embryos in 1985. This has had far reaching consequences for the science of cryobiology and society-at-large. His landmark paper in Nature with Gregory Fahy [15] is one of the most cited papers in cryobiology, having described the first demonstration of a broadly practical vitrification technology. Moreover, the fundamental knowledge provided in this paper was quickly applied to human fertility treatments, transforming the lives of millions of people worldwide. Sadly, his life and career were cut short by early-onset Alzheimer's disease in 2024, but his incredible legacy will remain. This editorial biography briefly describes Bill's scientific trajectory and the observations that led to the 1985 breakthrough, its implications and legacy, and our personal experiences of him as a friend and colleague. A full listing of Bill's contributions to cryobiology is provided in the Supplementary Information for this editorial.
Article Link https://www.sciencedirect.com/science/article/abs/pii/S0011224025000987


 
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